1- Blocking File Types:
a. Central Administration > Manage Web Applications > The MySite Web Application > “Blocked File Types” from the ribbon.
b. Add the extension you want in a new line.
2- Quota Limit Per User:
a. Create Personal Quota template.
b. Change Quota template for the Site Collection of the user
Central Admin > Application Management > Site Collections > Configure quotas and locks, or if you have large number of sites then use this PowerShell;
3- Set max upload size:
a. Central Admin > Manage Web Applications > The MySite Web Application > “General Settings” from the ribbon.
b. In the “Maximum upload size”, add the size.